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1223824-10mg 1223824-1mg

Pyrintegrin

Biogems

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DETAILS

  • Purity: ≥95%
  • Cas Number: 1228445-38-2
  • References: Shah, B. S. (2012). Pyrintegrin Induced Adipogenesis: Biology (Doctoral dissertation, Columbia University). Lee, H. W., Khan, S. Q., Faridi, M. H., Wei, C., Tardi, N. J., Altintas, M. M., ... & Gupta, V. (2015). A Podocyte-Based Automated Screening Assay Identifies Protective Small Molecules. Journal of the American Society of Nephrology, ASN-2014090859. Li, W., & Ding, S. (2011). Human pluripotent stem cells: decoding the naive state. Science translational medicine, 3(76), 76ps10-76ps10.
  • Application: FA
  • Formulation: Crystalline solid
  • Chemical Name: N-(cyclopropylmethyl)-4-[[4-(3,4-dihydro-6-hydroxy-1(2H)-quinolinyl)-2-pyrimidinyl]amino]-benzenesulfonamide
  • Molecular Weight: 451.5
  • Molecular Formula: C23H25N5O3S
  • Storage Conditions: Product should be kept at -20°C.
  • Pubchem Openeye Can Smiles: C1CC2=C(C=CC(=C2)O)N(C1)C3=NC(=NC=C3)NC4=CC=C(C=C4)S(=O)(=O)NCC5CC5

DESCRIPTION

Pyrintegrin is a Beta1 integrin activator that also activates a variety of other growth factor receptors. It is reported to aid in the survival of human embryonic stem cells after trypsin dissociation and enhance their adhesion to laminin and matrigel plates.