KLK14 Antibody (C-term) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 43847
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: KLK14
Other Names: Kallikrein-14, hK14, 3421-, Kallikrein-like protein 6, KLK-L6, KLK14, KLKL6
Availability: 2 weeks
Bio Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK14 is expressed by both benign and malignant glandular epithelial cells, thus exhibiting an expression pattern similar to that of two other prostatic kalikreins, KLK2 and KLK3.
Bio References: Brattsand, M., et al., J. Invest. Dermatol. 124(1):198-203 (2005).Yousef, G.M., et al., Prostate 56(4):287-292 (2003).Yousef, G.M., et al., Br. J. Cancer 87(11):1287-1293 (2002).Hooper, J.D., et al., Genomics 73(1):117-122 (2001).Yousef, G.M., et al., Cancer Res. 61(8):3425-3431 (2001).
Primary Accession: Q9P0G3
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP6333b was selected from the C-term region of human KLK14. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.