• Item: Anti-VPS35 Immunoassay Plate | 5X VPS35 Extraction Reagent | Recombinant VPS35 Standard | Standard and Sample Diluent (Red) | 10X Wash Buffer Concentrate | Anti-VPS35 Biotinylated Antibody Concentrate | Anti-VPS35 Biotinylated Antibody Diluent (Green) | 100X Streptavidin:HRP Concentrate | Streptavidin: HRP Diluent (Purple) | TMB Substrate | Stop Solution
• Target: VPS35
• Utility: ELISA kit used to quantitate VPS35 in samples.
• Category: Assay Kits
• Platform: Microplate
• Assay Type: Sandwich ELISA (Enzyme-linked Immunosorbent Assay)
• References: 1. Vilarino-Guell, C. et al. (2011) Am J Hum Genet 89:162–167 2. Zimprich, A. et al. (2011) Am J Hum Genet 89:168–175 3. Rahman, A.A., Morrison, B.E. (2019) Neurosci 401:1-10.
• Assay Range: 78.125 - 5000 pg/mL
• Description: Colorimetric measurement of VPS35
• Sensitivity: 50 pg/mL
• Component No: SKC-141A | SKC-141B | SKC-141C | SKC-141D | SKC-141F | SKC-141G | SKC-141H | SKC-141I | SKC-141J | SKC-141K
• Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
• Net Weight G: 500
• Product Type: ELISA Kits
• Sample Types: Tissue | Cell Lysate
• Stock Product: Y
• Quantity Size: 1 Plate | 1 bottle/10mL | 2 vials | 1 bottle/50mL | 1 bottle/100mL | 1 vial/150μL | 1 bottle/13mL | 1 vial/150μL | 1 bottle/13mL | 1 bottle/13mL | 1 bottle/13 mL
• Research Areas: Cell Signaling | Neuroscience |Neurodegeneration | Parkinson's Disease | Membrane Trafficking Proteins | Golgi Proteins | Protein Trafficking | Alzheimer's Disease
• Gross Weight Kg: 2
• Incubation Time: 3 hours
• Detection Method: Colorimetric Assay
• Alternative Names: Vacuolar protein sorting-associated protein 35, MEM3, PARK17, VPS35 retromer complex component, maternal-embryonic 3, vesicle protein sortin 35, TCCCTA00141, FLJ10752
• Cite This Product: VPS35 Kit (StressMarq Biosciences Inc., Victoria BC CANADA, Catalog # SKT-141)
• Country of Origin: Canada
• Number of Samples: 40 samples in duplicate
• Storage Temperature: 4ºC and -20ºC
• Shipping Temperature: Blue Ice
• Scientific Background: Vacuolar Protein Sorter-35 (VPS35) is a component of the retromer complex, which is essential for endosome-to-Golgi retrieval of membrane proteins. VPS35 mutations such as D620N have been linked to Parkinson’s Disease (PD) (1,2) and affect retromer function, protein homeostasis, and mitochondria (3).
• Species Reactivity Medium: Human | Mouse | Rat
• Species Reactivity Full Name: Human | Mouse | Rat

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