10012424
CAY10583
Cayman Chemical
DESCRIPTION
A potent, selective full agonist for BLT2 with an EC50 value of 20 nM; activates BLT2 at significantly lower concentrations than LTB4 (EC50 = 170 nM); dose dependently increases intracellular calcium stores and induces ERK phosphorylation in CHO cells expressing BLT2 with no effect on CHO cells expressing BLT1
DETAILS
- Inchi: InChI=1S/C25H25NO3/c1-2-3-13-24(27)26(21-9-5-4-6-10-21)18-19-14-16-20(17-15-19)22-11-7-8-12-23(22)25(28)29/h4-12,14-17H,2-3,13,18H2,1H3,(H,28,29)
- Purity: ≥98%
- Raptas: Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Immunology & Inflammation||Research Area|Lipid Biochemistry|Lipoxygenase Pathways
- Smiles: CCCCC(N(C1=CC=CC=C1)CC2=CC=C(C3=C(C(O)=O)C=CC=C3)C=C2)=O
- Inchikey: IUJTVDNJFPZYBL-UHFFFAOYSA-N
- Cas Number: 862891-27-8
- Formulation: A crystalline solid
- Storage Temp: -20
- Shipping Temp: -20
- Formula Markup: C25H25NO3
- Formula Weight: 387.5
- Shelf Life Days: 730
Equivalent Items
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