mouse monoclonal IgM; MCPIP Antibody (H-6) is an IgM κ mouse monoclonal MCPIP antibody (also designated ZC3H12A antibody, ZC12A antibody, Zinc Finger CCCH-Type Containing 12A antibody, Regnase-1 antibody, MCPIP1 antibody, Monocyte Chemotactic Protein-Induced Protein antibody, Endoribonuclease antibody, MCP-Induced Protein 1 antibody, MCPIP-1 antibody, Reg1 antibody, MCP Induced Protein 1 or Ribonuclease ZC3H12A antibody) that detects the MCPIP protein of mouse, rat and human origin by WB, IP, IF and ELISA. MCPIP Antibody (H-6) is available as the non-conjugated anti-MCPIP antibody. MCPIP (MCP-induced protein 1), also known as ZC3H12A (zinc finger CCCH-type containing 12A), is a 599 amino acid protein that localizes to the nucleus and contains one C3H1-type zinc finger. Functioning as a transcriptional activator, MCPIP triggers apoptosis and promotes MCP-1 and CJR-2B-induced angiogenesis, possibly playing a role in the development of acute monocytic leukemia. Overexpression of MCPIP is associated with ischemic heart disease, a condition characterized by reduced blood flow to the heart, often as a result of coronary artery disease. The gene encoding MCPIP maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome.

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.