7908985-50mg 7908985-5mg
D-AP5
Biogems
DESCRIPTION
D-AP5 is a selective N-methyl-D-aspartate (NMDA) receptor antagonist that binds at glutamate site. D-AP5 is reported to be the most active form of AP5 and is used in the research of synaptic plasticity.
DETAILS
- Purity: ≥95%
- Synonyms: 2-APV, 5 Phosphononorvaline
- Cas Number: 79055-68-8
- References: Steele, R. J., & Morris, R. G. M. (1999). Delay‐dependent impairment of a matching‐to‐place task with chronic and intrahippocampal infusion of the NMDA‐antagonist D‐AP5. Hippocampus, 9(2), 118-136. Morris, R. G. (1989). Synaptic plasticity and learning: selective impairment of learning rats and blockade of long-term potentiation in vivo by the N-methyl-D-aspartate receptor antagonist AP5. The Journal of neuroscience,9(9), 3040-3057. Davies, J., & Watkins, J. C. (1982). Actions of D and L forms of 2-amino-5-phosphonovalerate and 2-amino-4-phosphonobutyrate in the cat spinal cord.Brain research, 235(2), 378-386.
- Application: FA
- Formulation: Crystalline solid
- Chemical Name: (2R)-2-amino-5-phosphonopentanoic acid
- Molecular Weight: 197.1
- Molecular Formula: C5H12NO5P
- Storage Conditions: Product should be kept at -20°C.
- Pubchem Openeye Can Smiles: C(CC(C(=O)O)N)CP(=O)(O)O