mouse monoclonal IgG1; Exportin 7 Antibody (A-11) is an IgG1 κ mouse monoclonal Exportin 7 antibody (also designated Exportin-7 antibody or XPO7 antibody) that detects the Exportin 7 protein of mouse, rat and human origin by WB, IP, IF, IHC(P) and ELISA. Exportin 7 Antibody (A-11) is available as both the non-conjugated anti-Exportin 7 antibody form, as well as multiple conjugated forms of anti-Exportin 7 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Exportin 7 is also known as RanBP16 (ran-binding protein 16) or XPO7 and is a 1,087 amino acid protein. Exportin 7 is primarily expressed in testis, thyroid and bone marrow, but is also expressed in lung, liver and small intestine. Exportin 7 translocates proteins and large RNAs through the nuclear pore complex (NPC) and is localized to the cytoplasm and nucleus. Exportin 7 has two types of receptors, designated importins and exportins, both of which recognize proteins that contain nuclear localization signals (NLSs) and are targeted for transport either in or out of the nucleus via the NPC. Additionally, the nucleocytoplasmic RanGTP gradient regulates Exportin 7 distribution, and enables Exportin 7 to bind and release proteins and large RNAs before and after their transportation. Exportin 7 is thought to play a role in erythroid differentiation and may also interact with cancer-associated proteins, suggesting a role for Exportin 7 in tumorigenesis.

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.