DESCRIPTION

• Target: MAP4K4 (pThr187)
• Gene Id: 9448
• Conjugate: Unconjugated
• Immunogen: A phospho-specific peptide corresponding to residues surrounding Thr187 of human MAP4K4 (AA184-190)
• Swiss-prot: O95819
• Specificity: Detects 142.101 kDa.
• Applications: WB | AM
• Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
• Host Species: Rabbit
• Product Type: Polyclonal
• Purification: Peptide Affinity Purified
• Research Areas: Cell Signaling | Protein Phosphorylation | Serine / Threonine Kinases | MAPK Pathway
• Storage Buffer: PBS pH7.4, 50% glycerol, 0.025% Thimerosal *Storage buffer may change when conjugated
• Accession Number: NP_001155032
• Alternative Names: Hepatocyte progenitor kinase like/germinal center kinase like kinase Antibody, HGK Antibody, HPK/GCK like kinase Antibody, KIAA0687 Antibody, M4K4_HUMAN Antibody, MAP4K4 Antibody, MAPK/ERK kinase kinase kinase 4 Antibody, MEK kinase kinase 4 Antibody, MEKKK 4 Antibody, Mitogen activated protein kinase kinase kinase kinase 4 Antibody, Nck interacting kinase Antibody, NIK Antibody
• Antibody Dilution: WB (1:250); optimal dilutions for assays should be determined by the user.
• Cite This Product: StressMarq Biosciences Cat# SPC-994D, RRID: AB_2708291
• Immunogen Species: Human
• Tissue Specificity: Appears to be ubiquitous. Expressed in all tissue types examined. Isoform 5 appears to be more abundant in the brain. Isoform 4 is predominant in the liver, skeletal muscle and placenta.
• Storage Temperature: -20ºC
• Shipping Temperature: Blue Ice or 4ºC
• Cellular Localization: Cytoplasm
• Scientific Background: MAP4K4 appears to act upstream of the JUN N-terminal pathway. It phosphorylates SMAD1 on Thr-322.
• Certificate of Analysis: A 1:250 dilution of SPC-994 was sufficient for detection of MAP4K4 (pThr187) in 10 µg of HeLa cell lysate by ECL immunoblot analysis using goat anti-rabbit IgG:HRP as the secondary antibody.
• Species Reactivity Full Name: Human