HAMP Antibody (Center) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 57817
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: HAMP
Other Names: Hepcidin, Liver-expressed antimicrobial peptide 1, LEAP-1, Putative liver tumor regressor, PLTR, Hepcidin-25, Hepc25, Hepcidin-20, Hepc20, HAMP, HEPC, LEAP1
Availability: 2 weeks
Bio Background: HAMP is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta-sheet structures. These peptides exhibit antimicrobial activity.
Bio References: Matsumoto, M., et al. Circ. J. 74(2):301-306(2010)del Giudice, E.M., et al. J. Clin. Endocrinol. Metab. 94(12):5102-5107(2009)Kwapisz, J., et al. J Zhejiang Univ Sci B 10(11):791-795(2009)Barton, J.C., et al. Am. J. Hematol. 84(11):710-714(2009)Nemeth, E., et al. Acta Haematol. 122 (2-3), 78-86 (2009) Hunter, H.N., et al. J. Biol. Chem. 277(40):37597-37603(2002)Kluver, E., et al. J. Pept. Res. 59(6):241-248(2002)
Primary Accession: P81172