400-19
Recombinant Rat IL-10
PeproTech
DESCRIPTION
IL-10 is an immunosuppressive cytokine produced by a variety of mammalian cell types including macrophages, monocytes, T cells, B cells and keratinocytes. IL-10 inhibits the expression of proinflammatory cytokines such as IL-1 and TNF-alpha. Like IL-4, IL-10 enhances humoral immune responses and attenuates cell-mediated immune reactions. Human IL-10 is active on murine cells, but murine IL-10 is inactive on human cells. Recombinant Rat IL-10 is an 18.7 kDa protein of 160 amino acid residues.
DETAILS
- Gene Id: 25325
- Uniprot: P29456
- Activity: The ED50 as determined by the dose-dependent inhibition of antigen-specific T cell proliferation is ≤10ng/ml.
- Category: RUO Cytokines
- Subcategory: Growth Factors & Cytokines
- Research Areas: AIDS/HIV, Cancer, Immune System, Inflammation, Neurobiology, Stem Cells and Differentiation, Allergy, Transplantation, COVID-19
- Alternative Names: B-TCGF, CSIF, TGIF
- Species of Origin: Rat
- Expression System Source: E.coli
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