Mouse ASGR1 Protein, Fc Tag (MALS & SPR verified)

DESCRIPTION

This gene encodes a subunit of the asialoglycoprotein receptor. This receptor is a transmembrane protein that plays a critical role in serum glycoprotein homeostasis by mediating the endocytosis and lysosomal degradation of glycoproteins with exposed terminal galactose or N-acetylgalactosamine residues. The asialoglycoprotein receptor may facilitate hepatic infection by multiple viruses including hepatitis B, and is also a target for liver-specific drug delivery. The asialoglycoprotein receptor is a hetero-oligomeric protein composed of major and minor subunits, which are encoded by different genes. The protein encoded by this gene is the more abundant major subunit. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011]

DETAILS

Tag: N-Fc
Host: HEK293
Size: 1mg
Buffer: PBS, 0.2M Arginine, pH7.4
Format: Powder
Purity: 90%
Source: Mouse ASGR1 Protein, Fc Tag (AS1-M5255) is expressed from human 293 cells (HEK293). It contains AA Gln 61 - Asn 284 (Accession # P34927).
Storage: -20℃
Category: Other Recombinant Proteins
Molecule: ASGR1
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: Gln 61 - Asn 284
Swiss-prot: P34927
Package Size: 200ug*5
Characteristics: This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 52.2 kDa. The protein migrates as 38-43 kDa and 55-65 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 52.2 kDa
Shipping Condition: RT
Species Reactivity: Mouse
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