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Recombinant Murine PF-4 (CXCL4)



PF-4 is a CXC chemokine that is expressed in megakaryocytes and stored in the alpha-granules of platelets. PF-4 is chemotactic towards neutrophils and monocytes, and has been shown to inhibit angiogenesis. Recombinant Murine PF-4 is an 8.2 kDa protein containing 76 amino acid residues, including the four highly conserved residues present in CXC chemokines.


  • Gene Id: 56744
  • Uniprot: Q9Z126
  • Activity: Determined by its ability to chemoattract human neutrophils using a concentration range of 10.0-100.0 ng/ml.
  • Category: RUO Cytokines
  • Subcategory: Chemokines
  • Research Areas: Angiogenesis/Cardiovascular, Chemotaxis, Immune System, Inflammation, Wound Healing
  • Alternative Names: Platelet Factor-4, CXCL4, Oncostatin A, Ironplact
  • Species of Origin: Murine
  • Expression System Source: E.coli