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ILA-H82F1-25ug ILA-H82F1-200ug

Biotinylated Human IL-17 RA / CD217 Protein, Fc,Avitag™

ACROBiosystems

DESCRIPTION

Biotinylated Human IL-17 RA, Fc,Avitag (ILA-H82F1) is expressed from human 293 cells (HEK293). It contains AA Leu 33 - Trp 320 (Accession # Q96F46-1).

DETAILS

  • Tag: C-Fc & C-Avi
  • Host: HEK293
  • Size: 25ug
  • Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
  • Format: Powder
  • Purity: 95%
  • Storage: -20℃
  • Category: MABSol® Biotin Labeled Proteins
  • Molecule: IL-17 RA
  • Accession: NP_055154.3
  • Conjugate: Biotin-labeled
  • Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
  • Background: Interleukin 17 receptor A (IL17RA) is also known as cluster of differentiation w217 (CDw217), is a pro-inflammatory cytokine secreted by activated T-lymphocytes, belong to ubiquitous type I membrane glycoprotein, and binds with low affinity to interleukin 17A (IL17A). IL 17R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested . IL 17RA associates with IL 17RC to form a signaling receptor complex for IL 17 and IL 17F . Ligand and IL 17RA ligation promotes T cell activation and the production of IL - 6, G-CSF, SCF, and multiple pro-inflammatory chemokines. Defects in IL17RA are the cause of familial candidiasis type 5 (CANDF5).
  • Exp Region: Leu 33 - Trp 320
  • Swiss-prot: Q96F46-1
  • Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 61.9 kDa. As a result of glycosylation, the protein migrates as 80-115 kDa under reducing (R) condition, and 150-200 kDa under non-reducing (NR) condition (SDS-PAGE).
  • Endotoxin Level: 1.0 EU per μg
  • Molecular Weight: 61.9 kDa
  • Shipping Condition: RT
  • Species Reactivity: Human
  • Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html