Polyclonal Antibody to Myc (Phospho-Ser62)

DESCRIPTION

Participates in the regulation of gene transcription. Binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Seems to activate the transcription of growth-related genes. Baudino T A, et al. (2001) Mol Cell Biol. 21: 691-702. Blackwood E M, et al. (1991) Science. 251:1211-1217. Henriksson M, et al. (1996) Adv Cancer Res. 68: 109-182. Grandori C, et al. (2000) Annu Rev Cell Dev Biol. 16: 653-699.

DETAILS

Gene: MYC
App Id: WB,IF
Antigen: Myc (Phospho-Ser62)
Gene Id: 4609
Isotype: Rabbit IgG
Format Id: Purified
Uniprot Id: P01106
Host Animal: Rabbit
Clonality Id: Polyclonal
Reactivity Id: Human,Mouse,Rat
Product Content: Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Alternative Name: c-myc
Application Note: Predicted MW: 60kd, Immunofluorescence: 1:100~1:200
Storage Condition: Store the antibody at 4°C, stable for 6 months. For ong-term storage, store at -20°C. Avoid repeated freeze and thaw cycles.
Immunogen Information: Peptide sequence around phosphorylation site of serine 62 (P-L-S(p)-P-S) derived from Human Myc.