DHX36 Antibody

DETAILS

Buffer: DHX36 Antibody is supplied in PBS containing 0.02% sodium azide.
Isotype: IgG
Storage: DHX36 antibody can be stored at 4˚C for three months and -20˚C, stable for up to one year.
Category: Antibody
Shipping: Blue Ice
Clonality: Polyclonal
Conjugate: Unconjugated
Immunogen: Rabbit polyclonal DHX36 antibody was raised against a 19 amino acid peptide near the carboxy terminus of human DHX36.The immunogen is located within the last 50 amino acids of DHX36.
Swissprot: Q9H2U1
User Note: Optimal dilutions for each application to be determined by the researcher.
Background: DHX36 Antibody: DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure. DHX36 (DEAH box protein 36), also known as MLE-like protein 1 and RNA helicase associated with AU-rich element ARE (RHAU), belongs to RNA helicase of the DEAH family and may function in sex development and spermatogenesis. It is expressed in testis and is evolutionary conserved with true orthologs in almost all animal species. DHX36 plays a role in degradation and deadenylation of mRNAs containing in their 3'-UTR the consensus ARE sequence element. DHX36 is required for early embryogenesis.
Specificity: At least four isoforms of DDX36 are known to exist; this antibody will detect the three longest isoforms.
Host Species: Rabbit
Ncbi Gene Id: 170506
Purification: DHX36 Antibody is affinity chromatography purified via peptide column.
Concentration: 1 mg/mL
Modifications: None
Ncbi Organism: homo sapiens
Physical State: Liquid
Additional Names: DHX36 Antibody: G4R1, RHAU, DDX36, MLEL1, KIAA1488, Probable ATP-dependent RNA helicase DHX36, DEAH box protein 36
Application Note: DHX36 antibody can be used for detection of DHX36 by Western blot at 0.5 - 1 μg/mL.Antibody validated: Western Blot in mouse samples and Immunohistochemistry in human samples. All other applications and species not yet tested.
By Research Area: Stem Cell
Protein Accession: NP_065916
Protein Gi Number: 167830433
Ncbi Official Name: DEAH (Asp-Glu-Ala-His) box polypeptide 36
Positive Control 1: Cat. No. 1404 - Mouse Liver Tissue Lysate
Positive Control 2: Cat. No. 10-201 - Human Liver Tissue Slide
Species Reactivity: Human,Mouse
Tested Applications: ELISA,WB,IHC-P
Ncbi Official Symbol: DHX36
Predicted Molecular Weight: Predicted: 111 kDa