Anti-EpCAM Antibody

DESCRIPTION

The epithelial cell adhesion molecule Ep-CAM, which is also designated tumor-associated calcium signal transducer 1 and MK-1, is a monomeric membrane glycoprotein that is expressed in most normal human epithelium and carcinomas. The human Ep-CAM gene encodes a 314 amino acid protein that is expressed as two forms, a major form and a minor form, which are reduced upon treatment with the amino-glycosylation inhibitor tunicamycin. Ep-CAM is overexpressed in a variety of carcinomas and is, therefore, a potential target for the visualization and therapy of human solid tumors. Ep-CAM contains an extracellular domain containing two epidermal growth factor-like repeats, followed by a cysteine poor region, which is necessary for the adhesion properties of the molecule.

DETAILS

Host: Rabbit
Type: Primary
Uniprot: SwissProt: P16422 Human;SwissProt: Q99JW5 Mouse;SwissProt: O55159 Rat
Clonality: Rabbit polyclonal Antibody
Conjugate: Non-conjugated
Alias Names: 17 1A antibody 323/A3 antibody Adenocarcinoma associated antigen antibody Adenocarcinoma-associated antigen antibody Antigen identified by monoclonal antibody AUA1 antibody AUA1 antibody CD326 antibody CD326 antigen antibody Cell surface glycoprotein Trop 1 antibody Cell surface glycoprotein Trop 2 antibody Cell surface glycoprotein Trop-1 antibody CO 17A antibody CO17 1A antibody CO17A antibody DIAR5 antibody EGP 2 antibody EGP antibody EGP2 antibody EGP314 antibody EGP40 antibody Ep CAM antibody Ep-CAM antibody EPCAM antibody EPCAM_HUMAN antibody EpCAM1 antibody Epithelial cell adhesion molecule antibody Epithelial Cell Adhesion Molecule Intracellular Domain (EpCAM-ICD) antibody Epithelial cell surface antigen antibody Epithelial cellular adhesion molecule antibody Epithelial glycoprotein 1 antibody Epithelial glycoprotein 314 antibody Epithelial glycoprotein antibody ESA antibody GA733 1 antibody GA733 2 antibody GA733-2 antibody gastrointestinal tumor-associated antigen 2, 35-KD glycoprotein antibody gp4 antibody hEGP 2 antibody hEGP314 antibody HNPCC8 antibody Human epithelial glycoprotein 2 antibody KS 1/4 antigen antibody KS1/4 antibody KSA antibody Ly74 antibody Lymphocyte antigen 74 antibody M1S 1 antibody M1S2 antibody M4S1 antibody Major gastrointestinal tumor associated protein GA733 2 antibody Major gastrointestinal tumor-associated protein GA733-2 antibody mEGP314 antibody Membrane component chromosome 4 surface marker (35kD glycoprotein) antibody Membrane component, chromosome 4, surface marker 1 antibody Membrane component, chromosome 4, surface marker antibody MIC18 antibody MK 1 antibody Protein 289A antibody TACD1 antibody TACSTD1 antibody TROP1 antibody Tumor associated calcium signal transducer 1 antibody Tumor associated calcium signal transducer 2 precursor antibody Tumor-associated calcium signal transducer 1 antibody
Application: WB,IF-Cell,IHC-P
Epitope Region: Synthetic peptide within human EpCAM aa 90-180.
Protein Target: Ep-CAM, EGP, EGP314, hEGP314, EPCAM, GA733-2, M1S2, M4S1, MIC18, TACSTD1, TROP1
Target Species: Human,Mouse,Rat
Species Reactivity: Human,Mouse,Rat