Skip to Main Content
Welcome to the Scientist.com Marketplace

Go to Main Navigation

34597

Incyclinide

Cayman Chemical

Thumbnail image

DETAILS

  • Inchi: InChI=1S/C19H17NO7/c20-18(26)14-11(22)6-9-5-8-4-7-2-1-3-10(21)12(7)15(23)13(8)16(24)19(9,27)17(14)25/h1-3,8-9,21-22,24,27H,4-6H2,(H2,20,26)/t8-,9-,19-/m0/s1
  • Purity: ≥98%
  • Raptas: Product Type|Biochemicals|Small Molecule Inhibitors|MMPs||Research Area|Cancer|Cell Cycle|G1||Research Area|Cancer|Cell Death|Apoptosis||Research Area|Cell Biology|Proteolysis|Cytosolic & Secreted Proteases||Research Area|Endocrinology & Metabolism|Bone Growth & Remodeling
  • Smiles: OC1=C2[C@](CC3=CC=CC(O)=C3C2=O)([H])C[C@]4([H])[C@]1(C(C(C(N)=O)=C(C4)O)=O)O
  • Inchikey: ZXFCRFYULUUSDW-OWXODZSWSA-N
  • Cas Number: 15866-90-7
  • Formulation: A solid
  • Storage Temp: -20
  • Shipping Temp: -20
  • Formula Markup: C19H17NO7
  • Formula Weight: 371.3
  • Shelf Life Days: 1460

DESCRIPTION

An inhibitor of MMP-13, MMP-1, and MMP-8 (IC50s = 0.3, 34, and 48 µg/ml, respectively); inhibits chick osteoclast digestion of isolated bovine bone at 5 µg/ml and IL-1-induced glycosaminoglycan release from porcine articular cartilage explants at 10 µg/ml; induces cytotoxicity of HeLa and SiHa human cervical cancer cells