DESCRIPTION

• Aa: 2-136(end) with K27M mutation
• Mw: 16.2 kDa
• Tags: N-terminal His-tag
• Format: Aqueous buffer solution
• Genbank: NM_003532
• Species: Human
• Uniprot: P68431
• Mutation: K27M
• Shiptemp: -80°C (dry ice)
• Synonyms: Histone 3.1
• Warnings: Avoid freeze/thaw cycles. Storing diluted protein is not recommended, if necessary, use carrier protein (BSA 0.1 - 0.5%).
• Category: Methyltransferase/Substrates
• References: 1. Loyola, A., et al., Mol. Cell. 2006; 24(2): 309-316. 2. Khuong-Quang, D-A., et al., Acta. Neuropathol. 2012; 10.1007/s00401- 012-0998-0. Application Reference(s): Differential mode of antimicrobial actions of arginine-rich and lysine-rich histones against Gram-positive Staphylococcus aureus (2013)
• Description: Human Histone 3 (HIST1H3E), GenBank Accession No. NM_003532, a.a. 2-136(end) with K27M mutation and N-terminal His-tag, MW = 16.2 kDa, expressed in an E. coli expression system.
• Formulation: 8 mM PBS pH 7.4, 110 mM NaCl, 2.2 mM KCl and 20% glycerol
• Unspsc Code: 12352202
• Unspsc Name: Proteins
• Applications: Useful as a substrate for methyltransferases or acetyltransferases and for screening inhibitors and selectivity profiling for drug discovery.
• Product Type: Protein
• Host Cell Line: E. coli
• Biosafety Level: Not applicable (BSL-1)
• Related Products: 52016, 52013, 52010
• Storage Stability: At least 6 months at -80°C.
• Scientific Category: Methyltransferase