sc-365612 SAMPLE sc-365612
Promo Available
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PP2B-Aβ (A-11)
Santa Cruz Biotechnology
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DESCRIPTION
mouse monoclonal IgG1; PP2B-Aβ Antibody (A-11) is an IgG1 κ mouse monoclonal PP2B-A beta antibody (also designated PP2B-Aβ antibody) that detects the PP2B-A beta protein of mouse, rat and human origin by WB, IP, IF and ELISA. PP2B-Aβ Antibody (A-11) is available as both the non-conjugated anti-PP2B-A beta antibody form, as well as multiple conjugated forms of anti-PP2B-A beta antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunit have been identified, designated PP1, PP2A, PP2B and PP2C. An additional protein phosphatase catalytic subunit, PPX (also known as PP4), is a putative member of a novel PP family. The PP2B family comprises subfamily members PP2B-Aα, PP2B-Aβ and PP2B-Aγ. Two additional regulatory subunits been identified, designated PP2B-B1 and PP2B-B2.
DETAILS
- Host: mouse
- Type: Primary
- Uniprot: P16298
- Clonality: Monoclonal
- Conjugate: unconjugated
- Applications: WB, IP, IF, ELISA
- Human Gene Id: 5532
- Mouse Gene Id: 19056
- Protein Target: PP2B-Aβ
- Human Gene Name: PPP3CB
- Mouse Gene Name: Ppp3cb
- Species Reactivity: mouse, rat, human
PROMOTION TERMS
Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.
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