BIKE Antibody (Center) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 55589
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: BMP2K
Other Names: BMP-2-inducible protein kinase, BIKe, BMP2K, BIKE
Availability: 2 weeks
Bio Background: BIKE is the human homolog of mouse BMP-2-inducible kinase. Bone morphogenic proteins (BMPs) play a key role in skeletal development and patterning. Expression of the mouse gene is increased during BMP-2 induced differentiation and the gene product is a putative serine/threonine protein kinase containing a nuclear localization signal. Therefore, the protein encoded by this human homolog is thought to be a protein kinase with a putative regulatory role in attenuating the program of osteoblast differentiation.
Bio References: Kearns, A.E., et al., J. Biol. Chem. 276(45):42213-42218 (2001).Hoffmann, A., et al., Crit. Rev. Eukaryot. Gene Expr. 11 (1-3), 23-45 (2001).
Primary Accession: Q9NSY1
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP1723a was selected from the Center region of human BIKE . A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.