T2122
Ixazomib
TargetMol
DESCRIPTION
Ixazomib (MLN2238) , a second generation, boron-containing peptide proteasome inhibitor (PI), inhibits the chymotrypsin-like proteolytic (β5) site of the 20S proteasome (IC50/Ki: 3.4/0.93 nM, in cell-free assays), also inhibits the caspase-like (β1) and trypsin-like (β2) proteolytic sites (IC50: 31/3500 nM).
DETAILS
- Cas: 1072833-77-2
- Purity: 98.92%
- Smiles: C(NCC(N[C@@H](CC(C)C)B(O)O)=O)(=O)C1=C(Cl)C=CC(Cl)=C1
- Category: Compound
- Molecular Weight: 361.03
- Molecular Formula: C14H19BCl2N2O4
Lead Time: 4 - 5 weeks
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