DESCRIPTION

• Tag: C-Fc
• Host: HEK293
• Size: 1mg
• Buffer: Tris with Glycine, Arginine and NaCl, pH7.5
• Format: Powder
• Purity: 95%
• Storage: -20℃
• Category: Bio-Markers & CD Antigens
• Molecule: IL-3 R alpha
• Conjugate: Unconjugated
• Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
• Background: Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells.
• Exp Region: Thr 19 - Arg 305
• Swiss-prot: P26951-1
• Characteristics: This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 59.5 kDa. The protein migrates as 70-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Endotoxin Level: 1.0 EU per μg
• Molecular Weight: 59.5 kDa
• Shipping Condition: RT
• Species Reactivity: Human
• Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html