Pitstop2

DESCRIPTION

An inhibitor of the amphiphysin-clathrin interaction (IC50 = 12 μM); inhibits clathrin-mediated transferrin uptake in HeLa and U2OS cells (IC50s = 12-15 and 9.7 μM, respectively); inhibits HIV-1 entry and infectivity in HeLa reporter cell lines; inhibits clathrin-independent endocytosis of CD44, CD98, and CD147 in HeLa cells

DETAILS

Inchi: InChI=1S/C20H13BrN2O3S2/c21-15-10-8-13(9-11-15)12-17-19(24)22-20(27-17)23-28(25,26)18-7-3-5-14-4-1-2-6-16(14)18/h1-12H,(H,22,23,24)/b17-12-
Purity: ≥98%
Raptas: Product Type|Biochemicals||Research Area|Cell Biology|Endomembrane System & Vesicular Trafficking||Research Area|Immunology & Inflammation||Research Area|Infectious Disease|Viral Diseases|HIV & AIDS
Smiles: O=C1/C(SC(NS(C2=C(C=CC=C3)C3=CC=C2)(=O)=O)=N1)=C/C4=CC=C(Br)C=C4
Inchikey: CGDLWHGPJPVPDU-ATVHPVEESA-N
Cas Number: 1332879-52-3
Formulation: A crystalline solid
Storage Temp: -20
Shipping Temp: -20
Formula Markup: C20H13BrN2O3S2
Formula Weight: 473.4
Shelf Life Days: 1460