DESCRIPTION

• Aa: 24-186
• Mw: 44 kDa
• Tags: C-terminal Fc fusion (Human IgG1)
• Format: Aqueous buffer solution
• Genbank: NM_001561
• Species: Human
• Uniprot: Q07011
• Shiptemp: -80°C (dry ice)
• Synonyms: Tumor Necrosis Factor Receptor Superfamily member 9, TNFRSF9, ILA
• Warnings: Avoid freeze/thaw cycles. Protein may be diluted to ≥100 µg/ml in PBS + glycerol and stored at -80°C.
• Category: Immunotherapy/Protein
• References: 1. Wilcox, R.A., et al., J. Clin. Invest. 2002; 109(5): 651-659. 2. Foell, J. et al., J. Clin. Invest. 2003; 111(10): 1505-1518.
• Description: Human secreted CD137, Fc fusion protein, also known as Tumor Necrosis Factor Receptor Superfamily member 9, TNFRSF9, and ILA, GenBank Accession No. NM_001561, a.a. 24-186 expressed in a HEK293 cell expression system. MW = 44 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.
• Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol
• Unspsc Code: 12352202
• Unspsc Name: Proteins
• Applications: Useful for studying protein binding and screening small molecular inhibitors
• Product Type: Protein
• Biosafety Level: Not applicable (BSL-1)
• Endotoxin Level: <1 EU/µg
• Related Products: 71113, 71172, 71173, 71175
• Storage Stability: At least 6 months at -80°C.
• Scientific Category: Immunotherapy