Vaccinia Virus B18R Protein, His Tag

DESCRIPTION

B18R is a type I interferon (IFN)-binding protein and it is encoded by the B18R open reading frame in the WR (Western Reserve) strain of vaccinia virus, which contains two Ig-like C2-type domains and one Ig-like V-type domain. B18R exists in a soluble and a membrane-bound form. As a type I IFN receptor, B18R counteracts the antiviral effects of host IFN-alpha/beta. Also, B18R acts as a soluble IFN-alpha receptor and thus inhibits the interaction between host IFN-alpha and its receptor.

DETAILS

Tag: C-10×His
Host: HEK293
Size: 500ug
Buffer: PBS, pH7.4
Format: Powder
Purity: 90%
Source: Vaccinia Virus B18R, His Tag (B1R-H52H6) is expressed from human 293 cells (HEK293). It contains AA His 20 - Glu 351 (Accession # P25213).
Storage: -20℃
Category: Viral Proteins
Molecule: B18R
Conjugate: Unconjugated
Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Exp Region: His 20 - Glu 351
Swiss-prot: P25213
Package Size: 250ug*2
Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 40.3 kDa. The protein migrates as 50-65 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin Level: 1.0 EU per μg
Molecular Weight: 40.3 kDa
Shipping Condition: RT
Species Reactivity: Vaccinia Virus
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