CAY10650

DESCRIPTION

A highly potent (IC50 = 12 nM) cPLA2α inhibitor; demonstrates strong anti-inflammatory effects when applied topically at a dose of 0.1 mg/ear in a mouse model of acute irritant contact dermatitis

DETAILS

Inchi: InChI=1S/C28H25NO6/c1-18(2)27(31)25-16-29(26-13-8-19(28(32)33)14-24(25)26)15-20(30)17-34-21-9-11-23(12-10-21)35-22-6-4-3-5-7-22/h3-14,16,18H,15,17H2,1-2H3,(H,32,33)
Purity: ≥98%
Raptas: Product Type|Biochemicals|Small Molecule Inhibitors|Phospholipases||Research Area|Immunology & Inflammation||Research Area|Lipid Biochemistry|Glycerophospholipids|Phospholipases
Smiles: O=C(CN1C(C=CC(C(O)=O)=C2)=C2C(C(C(C)C)=O)=C1)COC3=CC=C(OC4=CC=CC=C4)C=C3
Inchikey: HTOJZPHWNDZOPQ-UHFFFAOYSA-N
Cas Number: 1233706-88-1
Formulation: A crystalline solid
Storage Temp: -20
Shipping Temp: -20
Formula Markup: C28H25NO6
Formula Weight: 471.5
Shelf Life Days: 730