10743
CAY10650
Cayman Chemical
DESCRIPTION
A highly potent (IC50 = 12 nM) cPLA2α inhibitor; demonstrates strong anti-inflammatory effects when applied topically at a dose of 0.1 mg/ear in a mouse model of acute irritant contact dermatitis
DETAILS
- Inchi: InChI=1S/C28H25NO6/c1-18(2)27(31)25-16-29(26-13-8-19(28(32)33)14-24(25)26)15-20(30)17-34-21-9-11-23(12-10-21)35-22-6-4-3-5-7-22/h3-14,16,18H,15,17H2,1-2H3,(H,32,33)
- Purity: ≥98%
- Raptas: Product Type|Biochemicals|Small Molecule Inhibitors|Phospholipases||Research Area|Immunology & Inflammation||Research Area|Lipid Biochemistry|Glycerophospholipids|Phospholipases
- Smiles: O=C(CN1C(C=CC(C(O)=O)=C2)=C2C(C(C(C)C)=O)=C1)COC3=CC=C(OC4=CC=CC=C4)C=C3
- Inchikey: HTOJZPHWNDZOPQ-UHFFFAOYSA-N
- Cas Number: 1233706-88-1
- Formulation: A crystalline solid
- Storage Temp: -20
- Shipping Temp: -20
- Formula Markup: C28H25NO6
- Formula Weight: 471.5
- Shelf Life Days: 730
Equivalent Items
| ... Loading