FLT3-IN-14

DESCRIPTION

FLT3-IN-14 is a potent inhibitor of FLT3, targeting FLT3-WT (IC50: 5.6 nM) and FLT3-ITD (IC50: 1.4 nM). It inhibits FLT3 (Y591) phosphorylation, arrests the cell cycle in the G1 phase, and induces apoptosis.

DETAILS

Cas: 2620551-45-1
Purity: 98%
Smiles: N(C(NC=1C=C(C(C)(C)C)ON1)=O)C2=CC=C(C3=CN4C=5C=6C(CCC5SC4=N3)=CNC6)C=C2
Category: Compound
Molecular Weight: 472.56
Molecular Formula: C25H24N6O2S

Lead Time: 5 + weeks