TMPH-01064
CCR4 Protein, Human, Recombinant (His & SUMO)
TargetMol
DESCRIPTION
High affinity receptor for the C-C type chemokines CCL17/TARC, CCL22/MDC and CKLF isoform 1/CKLF1. The activity of this receptor is mediated by G(i) proteins which activate a phosphatidylinositol-calcium second messenger system. Can function as a chemoattractant homing receptor on circulating memory lymphocytes and as a coreceptor for some primary HIV-2 isolates. In the CNS, could mediate hippocampal-neuron survival.
DETAILS
- Purity: 98%
- Category: Compound
- Molecular Weight: 19.0 kDa as predicted
Lead Time: 4 - 5 weeks
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