310-22
Recombinant Human AITRL
PeproTech
DESCRIPTION
AITRL, a member of the TNF superfamily, is expressed in endothelial cells, and signals through the AITR receptor. AITRL regulates T cell proliferation and survival, and effectuates the interaction between T lymphocytes and endothelial cells. The AITRL gene codes for a type II transmembrane protein comprised of 177 amino acids, including a 28 amino acid cytoplasmic region, a 21 amino acid transmembrane domain and a 128 amino acid extracellular domain. Recombinant Human soluble AITRL is a 14.4 kDa protein, containing 127 amino acid residues corresponding to the extracellular domain of AITRL.
DETAILS
- Gene Id: 8995
- Uniprot: Q9UNG2
- Activity: Determined by its ability to stimulate IL-8 production by human PBMC using a concentration range of 1.0-10.0 ng/ml. Please Note: Results may vary with PBMC donors.
- Category: RUO Cytokines
- Subcategory: Growth Factors & Cytokines
- Research Areas: Apoptosis, Immune System, Stem Cells and Differentiation, TNF Superfamily
- Alternative Names: Activation-Induced TNFR member Ligand, TNFSF18, GITRL, TL-6
- Species of Origin: Human
- Expression System Source: E.coli
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