SRPK1 Antibody (C-term) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 6732
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: SRPK1
Other Names: SRSF protein kinase 1, SFRS protein kinase 1, Serine/arginine-rich protein-specific kinase 1, SR-protein-specific kinase 1, SRPK1 {ECO:0000312|EMBL:CAC392991}
Availability: 2 weeks
Bio Background: This gene encodes a serine/arginine protein kinase specific for the SR (serine/arginine-rich domain) family of splicing factors. The protein localizes to the nucleus and the cytoplasm. It is thought to play a role in regulation of both constitutive and alternative splicing by regulating intracellular localization of splicing factors. A second alternatively spliced transcript variant for this gene has been described, but its full length nature has not been determined.
Bio References: Daub, H., et al., J. Virol. 76(16):8124-8137 (2002).Nikolakaki, E., et al., J. Biol. Chem. 276(43):40175-40182 (2001).Wang, H.Y., et al., Genomics 57(2):310-315 (1999).Papoutsopoulou, S., et al., Nucleic Acids Res. 27(14):2972-2980 (1999).Gui, J.F., et al., Nature 369(6482):678-682 (1994).
Other Accession: Q5R363
Primary Accession: Q96SB4
Targetspecificity: The synthetic peptide sequence used to generate the antibody AP7727b was selected from the C-term region of human SRPK1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.