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21408

(R,S)-CHPG

Cayman Chemical

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DETAILS

  • Inchi: InChI=1S/C8H8ClNO3/c9-6-2-1-4(11)3-5(6)7(10)8(12)13/h1-3,7,11H,10H2,(H,12,13)
  • Purity: ≥98%
  • Raptas: Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Neuroscience|Behavioral Neuroscience|Learning & Memory
  • Smiles: ClC1=C(C(N)C(O)=O)C=C(O)C=C1
  • Inchikey: UNIDAFCQFPGYJJ-UHFFFAOYSA-N
  • Cas Number: 170846-74-9
  • Formulation: A solid
  • Storage Temp: -20
  • Shipping Temp: -20
  • Formula Markup: C8H8ClNO3
  • Formula Weight: 201.6
  • Shelf Life Days: 730

DESCRIPTION

A potent and selective agonist at mGluR5; EC50 of 750 µM for calcium mobilization in CHO mGluR5a-expressing cells but was inactive in mGluR1a-expressing cells; in transfected HEK293 cells, (R,S)-CHPG bound mGluR1a and mGluR5a (Kis = 0.9 and 3.9 µM, respectively) but not ionotropic glutamate receptors