(R,S)-CHPG

DESCRIPTION

A potent and selective agonist at mGluR5; EC50 of 750 µM for calcium mobilization in CHO mGluR5a-expressing cells but was inactive in mGluR1a-expressing cells; in transfected HEK293 cells, (R,S)-CHPG bound mGluR1a and mGluR5a (Kis = 0.9 and 3.9 µM, respectively) but not ionotropic glutamate receptors

DETAILS

Inchi: InChI=1S/C8H8ClNO3/c9-6-2-1-4(11)3-5(6)7(10)8(12)13/h1-3,7,11H,10H2,(H,12,13)
Purity: ≥98%
Raptas: Product Type|Biochemicals|Receptor Pharmacology|Agonists||Research Area|Immunology & Inflammation|Innate Immunity||Research Area|Neuroscience|Behavioral Neuroscience|Learning & Memory
Smiles: ClC1=C(C(N)C(O)=O)C=C(O)C=C1
Inchikey: UNIDAFCQFPGYJJ-UHFFFAOYSA-N
Cas Number: 170846-74-9
Formulation: A solid
Storage Temp: -20
Shipping Temp: -20
Formula Markup: C8H8ClNO3
Formula Weight: 201.6
Shelf Life Days: 730