Ro 5126766

DESCRIPTION

RO5126766 (CH5126766) is a dual RAF/MEK inhibitor with IC50 of 8.2 nM, 19 nM, 56 nM, and 160 nM for BRAF V600E, BRAF, CRAF, and MEK1, respectively. Phase 1.

DETAILS

Cas: 946128-88-7
Purity: 98.3%
Smiles: CC=1C=2C(=CC(OC=3N=CC=CN3)=CC2)OC(=O)C1CC=4C(F)=C(NS(NC)(=O)=O)N=CC4
Category: Compound
Molecular Weight: 471.46
Molecular Formula: C21H18FN5O5S

Lead Time: 4 - 5 weeks