KCTD13 Antibody (C-term) Blocking Peptide

DETAILS

Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Gene Id: 253980
Category: Peptides; Blocking Peptides
Subtitle: Synthetic peptide
Gene Name: KCTD13
Other Names: BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1, hBACURD1, BTB/POZ domain-containing protein KCTD13, Polymerase delta-interacting protein 1, TNFAIP1-like protein, KCTD13, BACURD1, PDIP1, POLDIP1
Availability: 2 weeks
Bio Background: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration.
Bio References: Chen, Y., et al. Mol. Cell 35(6):841-855(2009)Tomaru, T., et al. Endocrinology 147(1):377-388(2006)Zhou, J., et al. J. Exp. Zoolog. Part A Comp. Exp. Biol. 303(3):227-240(2005)Wan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 101(44):15724-15729(2004)Kutsenko, A.S., et al. Nucleic Acids Res. 30(14):3163-3170(2002)
Primary Accession: Q8WZ19