Anti-GOT1 Antibody

DESCRIPTION

Biosynthesis of L-glutamate from L-aspartate or L-cysteine. Important regulator of levels of glutamate, the major excitatory neurotransmitter of the vertebrate central nervous system. Acts as a scavenger of glutamate in brain neuroprotection. The aspartate aminotransferase activity is involved in hepatic glucose synthesis during development and in adipocyte glyceroneogenesis. Using L-cysteine as substrate, regulates levels of mercaptopyruvate, an important source of hydrogen sulfide. Mercaptopyruvate is converted into H2S via the action of 3-mercaptopyruvate sulfurtransferase (3MST). Hydrogen sulfide is an important synaptic modulator and neuroprotectant in the brain.

DETAILS

Host: Rabbit
Type: Primary
Uniprot: SwissProt: P17174 Human
Clonality: Rabbit polyclonal Antibody
Conjugate: Non-conjugated
Alias Names: CGI-141 antibody GCT2 antibody Germ cell tumor 2 antibody Golgi transport 1 homolog B antibody Golgi transport 1B antibody GOLT1B antibody GOT1 antibody GOT1B_HUMAN antibody hGOT1a antibody Putative NF-kappa-B-activating protein 470 antibody Vesicle transport protein GOT1B antibody YMR292W antibody
Application: WB,IHC-P,FC
Epitope Region: Recombinant protein within N-terminal Human GOT1.
Protein Target: cAspAT, cCAT, GOT1
Target Species: Human
Species Reactivity: Human