E2656Mo
Mouse Growth Factor Receptor-Bound Protein 2, GRB2 ELISA Kit
Bioassay Technology Laboratory
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DESCRIPTION
Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. [Isoform 2]: Does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death.
DETAILS
- GeneID: 14784
- Species: Mouse
- Storage: 2-8ºC
- MASS(Da): 25,238
- Synonyms: Adapter protein GRB2;GRB 2;GRB2;Growth factor receptor-bound protein 2;SH2/SH3 adapter GRB2
- Assay Time: 1h 30m
- Assay Type: Sandwich
- Gene Names: GRB2
- Reactivity: Mouse
- Sample Type: Serum, plasma, cell culture supernates
- Sensitivity: 11.66ng/L
- Target Protein: GRB2
- Detection Range: 20-3800ng/L
- Full Product Name: Growth Factor Receptor-Bound Protein 2
- Standard Solution: 4000ng/L
- UniProt Accession: Q60631