E2656Mo
Mouse Growth Factor Receptor-Bound Protein 2, GRB2 ELISA Kit
Bioassay Technology Laboratory
DESCRIPTION
Adapter protein that provides a critical link between cell surface growth factor receptors and the Ras signaling pathway. [Isoform 2]: Does not bind to phosphorylated epidermal growth factor receptor (EGFR) but inhibits EGF-induced transactivation of a RAS-responsive element. Acts as a dominant negative protein over GRB2 and by suppressing proliferative signals, may trigger active programmed cell death.
DETAILS
- Gene Id: 14784
- Uniprot: Q60631
- Lead Time: 3 days
- Assay Type: Sandwich
- Sample Type: Serum, plasma, cell culture supernates
- Sensitivity: 11.66ng/L
- Detection Range: 20-3800ng/L
- Detection Method: ELISA
- Species Reactivity: Mouse