17921
9-Hydroxyellipticine (hydrochloride)
Cayman Chemical
DESCRIPTION
An ellipticine derivative with diverse biological activities; inhibits aroclor-induced activation of aniline hydroxylase, aminopyrine N-demethylase, and 7-ethoxycourmarin O-deethylase in rat liver microsomes (Kis = 3.5, 0.6, and 0.74 μM, respectively); inhibits the growth of L1210 murine leukemia cells (IC50 = 3 nM) in vitro and increases survival in an L1210 mouse leukemia model; inhibits carrageenan-induced edema and UV-induced erythema in guinea pigs
DETAILS
- Inchi: InChI=1S/C17H14N2O.ClH/c1-9-14-8-18-6-5-12(14)10(2)17-16(9)13-7-11(20)3-4-15(13)19-17;/h3-8,19-20H,1-2H3;1H
- Purity: ≥95%
- Raptas: Product Type|Biochemicals|Small Molecule Inhibitors||Research Area|Cancer||Research Area|Immunology & Inflammation
- Smiles: CC1=C2C(NC3=C2C=C(O)C=C3)=C(C)C4=C1C=NC=C4.Cl
- Inchikey: DLDKVFOKLGPVBT-UHFFFAOYSA-N
- Cas Number: 52238-35-4
- Formulation: A solid
- Storage Temp: -20
- Shipping Temp: -20
- Formula Markup: C17H14N2O • HCl
- Formula Weight: 298.8
- Shelf Life Days: 1460
Equivalent Items
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