Recombinant Murine FGF-basic

DESCRIPTION

FGF-basic is one of 23 known members of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-basic is a non-glycosylated, heparin-binding growth factor that is expressed in the brain, pituitary, kidney, retina, bone, testis, adrenal gland, liver, monocytes, epithelial cells and endothelial cells. FGF-basic signals through FGFR 1b, 1c, 2c, 3c and 4. Recombinant Murine FGF-basic is a 16.3 kDa protein consisting of 145 amino acid residues.

DETAILS

Gene Id: 14173
Uniprot: P15655
Activity: Determined by a cell proliferation assay using Balb/c 3T3 cells. The expected ED50 is ≤ 1.0 ng/ml, corresponding to a specific activity of ≥ 1 x 10^6 units/mg.
Category: RUO Cytokines
Subcategory: Growth Factors & Cytokines
Research Areas: Angiogenesis/Cardiovascular, Bone, Skeletal, Cartilage, Cancer, Cell Culture, FGF Superfamily, Immune System, Inflammation, Neurobiology, Stem Cells and Differentiation, Wound Healing, Organoids, Diabetes/Weight Regulation
Alternative Names: Fibroblast Growth Factor-basic, FGF-2, HBGF-2, Prostatropin
Species of Origin: Murine
Expression System Source: E.coli