12-1222-20 12-1222
Anti-Napsin A (Lung Adenocarcinoma Marker) Recombinant Rabbit Monoclonal Antibody (Clone:NAPSA/1865R)
Abeomics
DESCRIPTION
Napsin is a pepsin-like aspartic proteinaseconnected with maturation of surfactant protein B. There are two closely related napsins, napsin A and napsin B. Napsin A is expressed as a single chain protein. Immunohistochemical studies revealed high expression levels of napsin A in human lung and kidney but low expression in spleen. Napsin A is expressed in type II pneumocytes and in adenocarcinomas of lung. The high specificity expression of napsin A in adenocarcinomas of lung is useful to distinguish primary lung adenocarcinomas from adenocarcinomas of other organs.
DETAILS
- Gene: NAPSA
- App Id: IHC
- Gene Id: 9476
- Isotype: Rabbit IgG
- Format Id: Purified
- Clone Name: NAPSA/1865R
- Uniprot Id: O96009
- Host Animal: Rabbit
- Clonality Id: Monoclonal
- Purification: Protein A/G
- Reactivity Id: Human
- Product Content: 200µg/ml of recombinant MAb purified by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml.
- Alternative Name: ASP4, Aspartyl protease 4, KAP, Kidney derived aspartic protease like protein (Kdap), NAP1, NAPA, Napsa, napsin A aspartic peptidase, Pronapsin A, SNAPA
- Application Note: Immunohistochemistry (Formalin-fixed) (1-2µg/ml for 30 minutes at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes);
- Storage Condition: Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous.
- Immunogen Information: Recombinant human Napsin-A protein fragment (aa189-299) (exact sequence is proprietary)