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T21911

Rilmenidine (hemifumarate)

TargetMol

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DETAILS

  • Purity: 98%
  • Smiles: C1CC1C(C2CC2)NC3=NCCO3.C1CC1C(C2CC2)NC3=NCCO3.C(=C/C(=O)O)\C(=O)O
  • Category: Compounds
  • Cas Number: 207572-68-7
  • Molecular Weight: 238.28
  • Molecular Formula: C14H20N2O5

DESCRIPTION

Rilmenidine hemifumarate is an innovative antihypertensive agent that is an orally active, selective I1 imidazoline receptor agonist. Rilmenidine hemifumarate is an alpha 2-adrenoceptor agonist. Rilmenidine hemifumarate induces autophagy. Rilmenidine hemifumarate acts both centrally by reducing sympathetic overactivity and in the kidney by inhibiting the Na + /H + antiport. Rilmenidine hemifumarate modulates proliferation and stimulates the proapoptotic protein Bax thus inducing the perturbation of the mitochondrial pathway and apoptosis in human leukemic K562 cells [1] [2] [3].

Lead Time: 4 - 5 weeks

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