Bromoenol lactone

DESCRIPTION

BEL is a selective, irreversible, mechanism-based inhibitor of iPLA2 with a Ki value of 180 nM.{1631} It inhibits macrophage iPLA2 in a concentration-dependent manner with an IC50 value of 60 nM.{1291,1770}

DETAILS

Inchi: InChI=1S/C16H13BrO2/c17-10-12-8-9-15(16(18)19-12)14-7-3-5-11-4-1-2-6-13(11)14/h1-7,10,15H,8-9H2/b12-10+
Purity: ≥95%
Raptas: Product Type|Biochemicals|Small Molecule Inhibitors|Peptidases & Proteases||Product Type|Biochemicals|Small Molecule Inhibitors|Phospholipases||Research Area|Lipid Biochemistry|Glycerophospholipids|Phospholipases
Smiles: Br/C=C1\CCC(C(=O)O\1)c1cccc2ccccc12
Inchikey: BYUCSFWXCMTYOI-ZRDIBKRKSA-N
Cas Number: 88070-98-8
Formulation: A crystalline solid
Storage Temp: -20
Shipping Temp: -20
Formula Markup: C16H13BrO2
Formula Weight: 317.2
Shelf Life Days: 365