Human Cd59 Glycoprotein, CD59 ELISA Kit

DESCRIPTION

Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.

DETAILS

GeneID: 966
Species: Human
Storage: 2-8ºC
MASS(Da): 14,177
Synonyms: 1F5 antigen;20 kDa homologous restriction factor;CD 59;CD antigen CD59;CD59;CD59 glycoprotein;HRF20;HRF-20;MACIF;MAC-inhibitory protein;MAC-IP;MEM43 antigen;Membrane attack complex inhibition factor;Membrane inhibitor of reactive lysis;MIRL;Protectin
Assay Time: 1h 30m
Assay Type: Sandwich
Gene Names: CD59
Reactivity: Human
Sample Type: Serum, plasma, cell culture supernates
Sensitivity: 7.23ng/L
Target Protein: CD59
Detection Range: 10-2000ng/L
Full Product Name: Cd59 Glycoprotein
Standard Solution: 2400ng/L
UniProt Accession: P13987