300-36A
Recombinant Human MDC (CCL22) (69 a.a.)
PeproTech
DESCRIPTION
MDC is a CC chemokine that is produced in B cells, macrophages, monocyte-derived dendritic cells, activated NK cells and CD4 T cells. It signals through the CCR4 receptor. MDC chemoattracts monocytes, dendritic cells and NK cells, and exerts HIV-suppressive activity. The 67 amino acid form of MDC displays reduced chemoattractant activity, but retains HIV-suppressive activity. Recombinant Human MDC is an 8.1 kDa protein containing 69 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
DETAILS
- Gene Id: 6367
- Uniprot: O00626
- Activity: Determined by its ability to chemoattract human T cells using a concentration range of 10.0-100.0 ng/ml.
- Category: RUO Cytokines
- Subcategory: Chemokines
- Research Areas: AIDS/HIV, Chemotaxis, Immune System, Wound Healing
- Alternative Names: Macrophage-Derived Chemokine, CCL22, STCP-1, ABCD-1
- Species of Origin: Human
- Expression System Source: E.coli
Equivalent Items
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