mouse monoclonal IgG1; Endophilin B2 Antibody (A-10) is an IgG1 κ mouse monoclonal Endophilin B2 antibody (also designated SH3GLB2 antibody) that detects the Endophilin B2 protein of mouse, rat and human origin by WB, IP, IF and ELISA. Endophilin B2 Antibody (A-10) is available as both the non-conjugated anti-Endophilin B2 antibody form, as well as multiple conjugated forms of anti-Endophilin B2 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. The Endophilins comprise a family of proteins that associate with Amphiphysin, Synaptojanin and Dynamin and are implicated in presynaptic vesicle trafficking at nerve terminals. The expression patterns of the Endophilins are consistent with their cellular functions at the neuronal synapse. Endophilin B1 is a member of the B subgroup of the Endophilin family that is required for maintenance of mitochondrial morphology and for the regulation of the outer mitochondrial membrane dynamics. Endophilin B2 is also a member of the Endophilin B subroup that is ubiquitously expressed but shows highest levels in brain, adult lung, ovary, and spinal cord. Decreased levels of Endophilin B2 are found in Down Syndrome and may reflect brain dysgenesis.

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.