MEG (sulfate)

DESCRIPTION

MEG is a selective iNOS inhibitor and scavenger of peroxynitrite. The EC50 values for inhibition of iNOS (LPS-treated rat lung), eNOS (bovine endothelial), and nNOS (rat brain) are 11.5, 110, and 60 µM, respectively.{7417} MEG reacts with peroxynitrite with a second order rate constant of 1,900 M−1s−1 at 37°C.{4278} MEG has potent anti-inflammatory activity, which may be due to the combined effect of MEG acting as an inhibitor of iNOS and as a scavenger of peroxynitrite.{5922}

DETAILS

Purity: ≥98%
Raptas: Product Type|Biochemicals|Antioxidants||Product Type|Biochemicals|Small Molecule Inhibitors|Nitric Oxide Synthases||Research Area|Oxidative Stress & Reactive Species|Antioxidant Activity||Research Area|Oxidative Stress & Reactive Species|Reactive Nitrogen|iNOS
Smiles: N/C(N([H])CCS)=N/[H].O=S(O)(O)=O
Cas Number: 3979-00-8
Formulation: A crystalline solid
Storage Temp: 4
Shipping Temp: 4
Formula Markup: [C3H9N3S]2 • H2SO4
Formula Weight: 336.4
Shelf Life Days: 1460