Monoclonal Antibody to CD100 (Semaphorin-4D)(Clone : 133-1C6)

DESCRIPTION

Recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100 (Workshop VI; Code N-L026). It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.

DETAILS

Gene: SEMA4D
App Id: FACS,IF
Antigen: CD100 (Semaphorin-4D)
Gene Id: 10507
Isotype: Mouse IgM, kappa
Format Id: Purified
Clone Name: 133-1C6
Uniprot Id: Q92854
Host Animal: Mouse
Clonality Id: Monoclonal
Purification: Affinity Chromatography
Reactivity Id: Human
Product Content: 100 µg in 500 µl PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Alternative Name: SEMA4D||C9orf164||CD100||SEMAJ
Application Note: Flow Cytometry (1-2ug/million cells); Immunofluorescence (1-2ug/ml);
Storage Condition: Store the antibody at 4°C; stable for 6 months. For long-term storage; store at -20°C. Avoid repeated freeze and thaw cycles.
Immunogen Information: PHA stimulated human peripheral blood lymphocytes.