mouse monoclonal IgG1; RBM4 Antibody (E-3) is an IgG1 κ mouse monoclonal RBM4 antibody (also designated RBM4A antibody) that detects the RBM4 protein of mouse, rat and human origin by WB, IP, IF and ELISA. RBM4 Antibody (E-3) is available as both the non-conjugated anti-RBM4 antibody form, as well as multiple conjugated forms of anti-RBM4 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. RBM4 (RNA binding motif protein 4), also known as LARK, RBM4A, ZCRB3A or ZCCHC21, is a 364 amino acid protein that localizes to both the nucleus and the cytoplasm and contains one CCHC-type zinc finger and two RRM domains. Expressed ubiquitously, RBM4 interacts with Importin-12 (an association which results in the nuclear import of RBM4) and is thought to play a role in alternative splice site selection during pre-mRNA processing. RBM4 is down-regulated in patients affected with fetal Down syndrome (DS), suggesting that RBM4 may be involved in the regulation of normal brain development. Multiple isoforms of RBM4 exist due to alternative splicing events. RBM4B (RNA binding motif protein 4B), also known as RBM30, is a 359 amino acid protein that functions in a similar manner to RBM4 and is involved in the regulation of alternative splicing.

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.