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RC221799L4V

Scientist.com Supplier

Sec8 (EXOC4) (NM_001037126) Human Tagged ORF Clone Lentiviral Particle

Origene Technologies EU

DESCRIPTION

Lenti ORF particles, EXOC4 (mGFP-tagged) - Human exocyst complex component 4 (EXOC4), transcript variant 2, 200ul, >10^7 TU/mL

DETAILS

  • Mw: 53.7 kDa
  • Tag: mGFP
  • Accn: NM_001037126
  • Type: Human Tagged ORF Clone Lentiviral Particle
  • Refseq: NM_001037126.1, NP_001032203.1
  • Status: 7 Weeks*
  • Symbol: Sec8
  • Vector: pLenti-C-mGFP-P2A-Puro
  • Category: cDNA Clones
  • Locus Id: 60412
  • Orf Size: 1419 bp
  • Synonyms: SEC8; SEC8L1; Sec8p
  • Refseq Orf: 1422 bp
  • Refseq Size: 1620 bp
  • Availability: 7 Weeks
  • Cytogenetics: 7q33
  • Gene Summary: The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
  • Sequence Data: ORF Nucleotide Sequence ( show hide ) The ORF insert of this clone is exactly the same as(RC221799).
  • Oti Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
  • Oti Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
  • Protein Pathways: Tight junction
  • Mammalian Cell Selection: Puromycin