Anti-CD129 / IL-9R alpha Monoclonal Antibody (Clone:AH9R7)

DESCRIPTION

CD129 serves as the high affinity alpha subunit of IL-9 receptor. It associates with CD132, the common gamma chain shared by receptors of many different cytokines. CD129 is expressed at low levels by T and B cells, blood cell progenitors, eosinophils, mast cells, epithelial cells, muscle cells and neurons. Its signaling (through JAK/STAT pathways) results in proliferative and anti-apoptotic response, which is critical e.g. for intrathymic T cell development and survival of various cell types. The gene for CD129 is located at the pseudoautosomal regions of X and Y chromosomes and it may be related with the development of asthma.

DETAILS

Gene: IL9R
App Id: FACS, ELISA, Functional Assay
Antigen: CD129 / IL-9R alpha
Gene Id: 3581
Isotype: Mouse IgG2b
Format Id: Purified
Clone Name: AH9R7
Uniprot Id: Q01113
Host Animal: Mouse
Clonality Id: Monoclonal
Purification: Purified by protein-A affinity chromatography
Reactivity Id: Human
Alternative Name: IL9R
Application Note: Flow Cytometry Application note:it is recommended to use bright fluorochromes or signal multiplying detection ELISA Functional Application blocking
Storage Condition: Store at 2-8°C. Do not freeze.
Immunogen Information: Human CD129-transfected cell line