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CDA-C52H4-50ug CDA-C52H4-1mg

Cynomolgus CD8 alpha / CD8A Protein, His Tag (MALS verified)

ACROBiosystems

DETAILS

  • Tag: C-10×His
  • Host: HEK293
  • Size: 1mg
  • Buffer: PBS, pH7.4
  • Format: Powder
  • Purity: 95%
  • Storage: -20℃
  • Category: Bio-Markers & CD Antigens
  • Molecule: CD8 alpha
  • Conjugate: Unconjugated
  • Stability: ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
  • Background: Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Src kinase LCK to the vicinity of the TCR-CD3 complex. In NK-cells, the presence of CD8A homodimers at the cell surface provides a survival mechanism allowing conjugation and lysis of multiple target cells. CD8A homodimer molecules also promote the survival and differentiation of activated lymphocytes into memory CD8 T-cells.
  • Exp Region: Asn 63 - Asp 223
  • Swiss-prot: XP_005575419.2
  • Characteristics: This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 19.6 kDa. The protein migrates as 20-30 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
  • Endotoxin Level: 1.0 EU per μg
  • Molecular Weight: 19.6 kDa
  • Shipping Condition: RT
  • Species Reactivity: Cynomolgus
  • Extra Shippinghandling Fee: Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/A48-Shipping-and-Payments.html

DESCRIPTION

Cynomolgus CD8 alpha Protein, His Tag (CDA-C52H4) is expressed from human 293 cells (HEK293). It contains AA Asn 63 - Asp 223 (Accession # XP_005575419.2).