mouse monoclonal IgG1; pS2 Antibody (A-10) is an IgG1 κ mouse monoclonal pS2 antibody (also designated pS2 antibody) that detects the pS2 protein of human origin by WB, IP, IF and ELISA. pS2 Antibody (A-10) is available as both the non-conjugated anti-pS2 antibody form, as well as multiple conjugated forms of anti-pS2 antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Trefoil peptides are protease resistant molecules secreted throughout the gut that play a role in mucosal healing. These peptides contain three intrachain disulfide bonds, forming the trefoil motif, or P-domain. pS2, also designated Md2, BCEI, TFF1 and pNR-2, is a trefoil protein that is highly expressed in normal gastric mucosa. pS2 has also been detected in a number of carcinomas including cancers of the breast, pancreas and stomach. pS2 is not present in normal breast tissue but is inducible by estrogen in MCF7 cells. pS2 is known to form dimers and this dimerization is thought to play a role in its protective and healing properties. The gene encoding pS2 maps to human chromosome 21q22.3.

Free sample available. Limit 3 free samples for each full size Santa Cruz Biotechnology primary antibody ordered. All samples must be different. Customer responsible for shipping costs.